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Chemical Structure : BMS-22
CAS No.: 445479-97-0
Catalog No.: PC-60324Not For Human Use, Lab Use Only.
BMS-22 is a potent, selective, allosteric CCR2 antagonist with binding IC50 of 5.1 nM.
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|---|---|---|---|
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
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BMS-22 is a potent, selective, allosteric CCR2 antagonist with binding IC50 of 5.1 nM.
BMS-22 displays potent functional antagonism (calcium flux IC50=18 nM and chemotaxis IC 50=1 nM).
| M.Wt | 593.66 | |
| Formula | C28H34F3N5O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-[(isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide |
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1. Zweemer AJ, et al. Mol Pharmacol. 2013 Oct;84(4):551-61.
2. Cherney RJ, et al. J Med Chem. 2008 Feb 28;51(4):721-4.
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