Chemical Structure : BMS-3
CAS No.: 1338247-30-5
Catalog No.: PC-45450Not For Human Use, Lab Use Only.
BMS-3 is a potent LIMK inhibitor with IC50 of 5/6 nM for LIMK1/2.
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BMS-3 is a potent LIMK inhibitor with IC50 of 5/6 nM for LIMK1/2.
BMS-3 shows cytotoxic effect and inhibits the proliferation of A549 cells with IC50 of 154 nM.
M.Wt | 429.2712 | |
Formula | C17H12Cl2F2N4OS | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 30 mg/mL |
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Chemical Name/SMILES |
Cyclopropanecarboxamide, N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]- |
1. Ross-Macdonald P, et al. Mol Cancer Ther. 2008 Nov;7(11):3490-8.
2. Romarowski A, et al. Dev Biol. 2015 Sep 15;405(2):237-49.
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