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BMS-3

Chemical Structure : BMS-3

CAS No.: 1338247-30-5

BMS-3 (BMS3;BMS 3)

Catalog No.: PC-45450Not For Human Use, Lab Use Only.

BMS-3 is a potent LIMK inhibitor with IC50 of 5/6 nM for LIMK1/2.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BMS-3 is a potent LIMK inhibitor with IC50 of 5/6 nM for LIMK1/2.
BMS-3 shows cytotoxic effect and inhibits the proliferation of A549 cells with IC50 of 154 nM.

Physicochemical Properties

M.Wt 429.2712
Formula C17H12Cl2F2N4OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

Cyclopropanecarboxamide, N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-

References

1. Ross-Macdonald P, et al. Mol Cancer Ther. 2008 Nov;7(11):3490-8.

2. Romarowski A, et al. Dev Biol. 2015 Sep 15;405(2):237-49.

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