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Request The Product List ofLIM Kinase (LIMK) LIM Kinase (LIMK)

Cat. No. Product Name Information
PC-49369

TH470

LIMK inhibitor

TH470 (TH-470) is a potent, highly selective type II LIMK1/2 inhibitor with cellular IC50 of 9.8 and 13 nM, respectively.
PC-38206

LMTK3 inibitor C28

LMTK3 inhibitor

LMTK3 inibitor C28 is a potent, ATP-competitive small-molecule inhibitor of lemur tyrosine kinase 3 (LMTK3) with IC50 of 67 nM.
PC-35851

TH-257

LIMK1/2 inhibitor

TH-257 (TH257) is a potent, selective, allosteric inhibitor of LIMK1 and LIMK2 with IC50 of 84 nM for LIMK1 and 39 nM for LIMK2 in a RapidFire MS assay.
PC-35249

LIMK1 and 2 dual inhibitor 1

LIMK1/2 inhibitor

LIMK1 and 2 dual inhibitor 1 (LIMK1/2-IN-1) is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM).
PC-35194

SR7826

LIMK1 inhibitor

SR7826 is a potent and selective LIM kinase (LIMK) inhibitor with IC50 of 43 nM (LIMK1), displays >100-fold selectivity over ROCK1 and ROCK2, as well as JNK kinases (>400-fold).
PC-43141

LX7101

LIMK/ROCK inhibitor

LX7101 is a potent, dual LIMK and ROCK inhibitor with IC50 of 4.3/32//69/32/ nM for LIMK2/LIMK1/ROCK1/ROCK2, respectively.
PC-60271

R-10015

LIMK1 inhibitor

R-10015 (R10015) is a potent, selective inhibitor of human LIMK1 with IC50 of 38 nM.
PC-70101

CRT-0105950

LIMK inhibitor

CRT-0105950 (CRT0105950) is a novel potent LIMK inhibitor with IC50 of 0.3 nM and 1 nM for LIMK1 and LIMK2, respectively.
PC-70100

CRT-0105446

LIMK inhibitor

CRT-0105446 (CRT0105446) is a novel potent LIMK inhibitor with IC50 of 8 nM and 32 nM for LIMK1 and LIMK2, respectively.
PC-70099

Pyr-1

LIMK inhibitor

Liminib (Pyr-1) is a novel potent, selective, cell permeable and ATP competitive LIMK inhibitor.
PC-70098

LIMK-IN-14

LIMK inhibitor

LIMK-IN-14 is a potent, selective LIMK inhibitor with IC50 of 0.9 nM and 0.5 nM and 1.2 nM for LIMK1 and LIMK2, respectively.
PC-70097

LIMK-IN-22j

LIMK inhibitor

LIMK-IN-22j (LIMK-IN-1) is a potent, selective LIMK inhibitor with IC50 of 3.2 nM and 1.2 nM for LIMK1 and LIMK2, respectively.

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