LIJTF500025 | LIMK1/2, RIPK1 inhibitor

Chemical Structure : LIJTF500025

Catalog No.: PC-24386Not For Human Use, Lab Use Only.

LIJTF500025 is a potent, allosteric LIMK1/2 and RIPK1 dual inhibitor with EC50 of 82/40 nM and 7.85 nM respectively in NanoBRET assays.

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Biological Activity

LIJTF500025 is a potent, allosteric LIMK1/2 and RIPK1 dual inhibitor with EC50 of 82/40 nM and 7.85 nM respectively in NanoBRET assays.

M.Wt	479.92
Formula	C24H22ClN5O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-benzyl-6-(8-chloro-5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-7-oxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-3-carboxamide

1. Mandel S, et al. ACS Chem Biol. 2025 Apr 14. doi: 10.1021/acschembio.5c00097.