Chemical Structure : BMS-345541
CAS No.:
445430-58-0
BMS-345541
(BMS345541, BMS 345541)
Catalog No. : PC-42632Not For Human Use, Lab Use Only.
BMS-345541 is a potent and selective IKK-2 inhibitor with IC50 of 0.3 uM, less potent for IKK-1 (IC40=4 uM) and no activity against IKK-ε.
Packing Price Stock Quantity 10 mg $128 In stock 0 1 2 3 4 5 25 mg $218 In stock 0 1 2 3 4 5 50 mg $358 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4263201
Biological Activity
BMS-345541 is a potent and selective IKK-2 inhibitor with IC50 of 0.3 uM, less potent for IKK-1 (IC40=4 uM) and no activity against IKK-ε.
Physicochemical Properties
M.Wt
255.3183
Formula
C14H17N5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1,2-Ethanediamine, N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-
References
1. Burke JR, et al. J Biol Chem
2. McIntyre KW, et al. Arthritis Rheum
3. López-Guerra M, et al. Clin Cancer Res
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