Catalog No.: PC-42693Not For Human Use, Lab Use Only.
BMS-687453 (BMS687453) is a potent and selective PPARα agonist with EC50 of 10 nM for human PPARα and 410-fold selectivity over human PPARγ in PPAR-GAL4 transactivation assays.
BMS-687453 (BMS687453) is a potent and selective PPARα agonist with EC50 of 10 nM for human PPARα and 410-fold selectivity over human PPARγ in PPAR-GAL4 transactivation assays.
BMS-687453 has negligible cross-reactivity against a panel of human nuclear hormone receptors including PPARδ.
BMS-687453 demonstrates an excellent pharmacological and safety profile for the treatment of atherosclerosis and dyslipidemia.
