Chemical Structure : BMS-813160
CAS No.: 1286279-29-5
Catalog No.: PC-72668Not For Human Use, Lab Use Only.
BMS-813160 (BMS 813160) a potent and selective CCR2/5 dual antagonist with binding IC50 of 6.2/3.6 nM, respectively.
Packing | Price | Stock | Quantity |
---|---|---|---|
5 mg | $138 | In stock | |
10 mg | $218 | In stock | |
25 mg | $378 | In stock | |
50 mg | $588 | In stock | |
100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
BMS-813160 (BMS 813160) a potent and selective CCR2/5 dual antagonist with binding IC50 of 6.2/3.6 nM, respectively.
BMS-813160 had excellent oral bioavailability and exhibited low clearance in dog and cyno.
BMS-813160 inhibited the migration of inflammatory monocytes and macrophages in the mouse thioglycollate-induced peritonitis model.
M.Wt | 484.649 | |
Formula | C25H40N8O2 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
N-((1R,2S,5R)-2-((S)-3-((7-(tert-butyl)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)-2-oxopyrrolidin-1-yl)-5-(tert-butylamino)cyclohexyl)acetamide |
1. Cherney RJ, et al. ACS Med Chem Lett. 2021 Oct 15;12(11):1753-1758.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright