Chemical Structure : BMS-911543
CAS No.:
1271022-90-2
BMS-911543
(BMS911543;BMS 911543)
Catalog No. : PC-44289Not For Human Use, Lab Use Only.
BMS-911543 is a potent and selective small-molecule inhibitor of JAK2 with IC50 of 1.1 nM.
Packing Price Stock Quantity 5 mg $118 In stock 0 1 2 3 4 5 10 mg $188 In stock 0 1 2 3 4 5 25 mg $328 In stock 0 1 2 3 4 5 50 mg $548 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4428901
Biological Activity
BMS-911543 is a potent and selective small-molecule inhibitor of JAK2 with IC50 of 1.1 nM.
Physicochemical Properties
M.Wt
432.5214
Formula
C23H28N8O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Imidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide,N,N-dicyclopropyl-4-[(1,5-dimethyl-1H-pyrazol-3-yl)amino]-6-ethyl-1,6-dihydro-1-methyl-
References
1. Purandare AV, et al. Leukemia
2. Wan H, et al. ACS Med Chem Lett
3. Mace TA, et al. Oncotarget
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