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BMS-952048

Chemical Structure : BMS-952048

CAS No.: 1375751-32-8

BMS-952048 (BMS952048, BMS 952048)

Catalog No.: PC-35963Not For Human Use, Lab Use Only.

BMS-952048 is a positive allosteric modulator of mGluR5 with EC50 of 10 nM.

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    Biological Activity

    BMS-952048 is a positive allosteric modulator of mGluR5 with EC50 of 10 nM.

    Physicochemical Properties

    M.Wt 377.351
    Formula C21H13F2N3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (4R,5R)-5-(4-fluorophenyl)-4-(5-((3-fluoropyridin-2-yl)ethynyl)pyridin-3-yl)oxazolidin-2-one

    References

    1. Huang H, et al. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4165-9.

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