Afimetoran (BMS-986256) | TLR7/8 inhibitor

You are here:Home-Chemical Inhibitors & Agonists-Immunology/Inflammation-Toll-like Receptor (TLR)-BMS-986256

Chemical Structure : BMS-986256

CAS No.: 2171019-55-7

BMS-986256 (Afimetoran, BMS986256)

Catalog No.: PC-72474Not For Human Use, Lab Use Only.

BMS-986256 (Afimetoran, BMS986256) is an orally active, potent and selective inhibitor antagonist of TLR7/8.

Packing	Price	Stock
5 mg	$188	In stock
10 mg	$298	In stock
25 mg	$498	In stock
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BMS-986256 (Afimetoran, BMS986256) is an orally active, potent and selective inhibitor antagonist of TLR7/8.
BMS-986256 has demonstrated efficacy in animal models of lupus as well as favorable PK and acceptable safety profiles in healthy subjects.

Physicochemical Properties

M.Wt	444.6
Formula	C26H32N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[4-[2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-propan-2-yl-1H-indol-5-yl]piperidin-1-yl]acetamide

References

1. U Ranganathan et al. PO.6.132 A phase 2b study of afimetoran (BMS-986256) in patients with active systemic lupus erythematosus (SLE): optimization of a lupus clinical trial design.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

BMS-986256 (Afimetoran, BMS986256)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.