Catalog No.: PC-70293Not For Human Use, Lab Use Only.
BMS493 (BMS-204493) is a potent, pan-RAR inverse agonist that blocks RARα activity with IC50 of 114 nM, also is an agonist of orphan nuclear receptor tailless (TLX, NR2E1) with EC50 of 54 nM.
BMS493 (BMS-204493) is a potent, pan-RAR inverse agonist that blocks RARα activity with IC50 of 114 nM, also is an agonist of orphan nuclear receptor tailless (TLX, NR2E1) with EC50 of 54 nM.
BMS-204493 (BMS493) prevents the recruitment of transcriptional coactivators to RARs while stabilizing corepressor interactions.
BMS-204493 (BMS493) blocks the ATRA-induced vasorelaxation.
