Catalog No.: PC-61069Not For Human Use, Lab Use Only.
BMT-145027 is a potent, selective, non-MPEP site mGluR5 positive allosteric modulator with EC50 of 47 nM, without inherent mGluR5 agonist activity (EC50>16 uM).
BMT-145027 is a potent, selective, non-MPEP site mGluR5 positive allosteric modulator with EC50 of 47 nM, without inherent mGluR5 agonist activity (EC50>16 uM).
BMT-145027 does not engage the receptor at the MPEP and CPPHA allosteric sites.
BMT-145027 improves cognition in a preclinical rodent model of learning and memory.
