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Chemical Structure : BN82002
Catalog No.: PC-60249Not For Human Use, Lab Use Only.
BN82002 is a potent Cdc25 dual specificity phosphatase inhibitor with IC50 of 2-6 uM for Cdc25A/B/C.
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BN82002 is a potent Cdc25 dual specificity phosphatase inhibitor with IC50 of 2-6 uM for Cdc25A/B/C.
BN82002 impairs the proliferation of tumoral cell lines and increases CDK1 inhibitory tyrosine phosphorylation, delays cell cycle progression in HeLa cells;.
BN82002 reduces growth rate of human tumor xenografts in mice.
| M.Wt | 359.426 | |
| Formula | C19H25N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Brezak MC, et al. Cancer Res. 2004 May 1;64(9):3320-5.
2. Contour-Galcéra MO, et al. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5809-12.
3. Brenner AK, et al. Molecules. 2017 Mar 11;22(3). pii: E446.
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