Chemical Structure : BN82002 hydrochloride
CAS No.: 1049740-43-3
Catalog No.: PC-22998Not For Human Use, Lab Use Only.
BN82002 hydrochloride is a potent Cdc25 dual specificity phosphatase inhibitor with IC50 of 2-6 uM for Cdc25A/B/C.
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BN82002 hydrochloride is a potent Cdc25 dual specificity phosphatase inhibitor with IC50 of 2-6 uM for Cdc25A/B/C.
BN82002 impairs the proliferation of tumoral cell lines and increases CDK1 inhibitory tyrosine phosphorylation, delays cell cycle progression in HeLa cells;.
BN82002 reduces growth rate of human tumor xenografts in mice.
M.Wt | 395.88 | |
Formula | C19H26ClN3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Phenol, 4-(dimethylamino)-2-methoxy-6-[[methyl[2-(4-nitrophenyl)ethyl]amino]methyl]-, hydrochloride (1:1) |
1. Brezak MC, et al. Cancer Res. 2004 May 1;64(9):3320-5.
2. Contour-Galcéra MO, et al. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5809-12.
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