BOLD-100 (KP-1339, IT-139) |CAS:197723-00-5 Probechem Biochemicals

Chemical Structure : BOLD-100

CAS No.:

BOLD-100 (KP-1339, IT-139, NKP-1339)

Catalog No.: PC-60227Not For Human Use, Lab Use Only.

A promising ruthenium anticancer compound that blocks angiogenesis, endothelial cell proliferation and migration stimulated by VEGF or NO donor agent.

Packing	Price	Stock
5 mg	$148	In stock
10 mg	$228	In stock
25 mg	$398	In stock
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Biological Activity

BOLD-100 (KP-1339, IT-139, NKP-1339) is a promising ruthenium anticancer compound that blocks angiogenesis, endothelial cell proliferation and migration stimulated by VEGF or NO donor agent.
BOLD-100 potentiates the anticancer activity of sorafenib in vitro and in vivo.
BOLD-100 overcomes GRP78-mediated chemoresistance, restores sensitivity to cytotoxic drugs in drug-resistant PDAC cells in vitro and in vivo.

Physicochemical Properties

M.Wt	502.138
Formula	C14H12Cl4N4NaRu
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

References

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BOLD-100 (KP-1339, IT-139, NKP-1339)

Biological Activity

Physicochemical Properties

References

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