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Chemical Structure : BRACO-19
Catalog No.: PC-63060Not For Human Use, Lab Use Only.
BRACO-19 is a potent small molecule Telomerase inhibitor (IC50=115 nM) that inhibits expression of human telomerase reverse transcriptase (hTERT).
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BRACO-19 is a potent small molecule Telomerase inhibitor (IC50=115 nM) that inhibits expression of human telomerase reverse transcriptase (hTERT).
BRACO-19 induces cellular senescence and inhibits growth of uterine cancer cells in vitro.
BRACO-19 inhibits growth of uterine tumor xenografts in vivo.
| M.Wt | 703.15 | |
| Formula | C35H46Cl3N7O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gowan SM, et al. Mol Pharmacol. 2002 May;61(5):1154-62.
2. Burger AM, et al. Cancer Res. 2005 Feb 15;65(4):1489-96.
3. Incles CM, et al. Mol Pharmacol. 2003 Nov;64(5):1101-8.
4. Gunaratnam M, et al. Biochem Pharmacol. 2009 Jul 15;78(2):115-22.
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