| Cat. No. |
Product Name |
Information |
| PC-49795 |
Teloxantron
Telomerase inhibitor
|
Teloxantron (Telomerase inhibitor TXT4) is a potent small molecule inhibitor of telomerase activity with IC50 of 9.61 uM, 7-fold lower than BIBR1532 (Cat# PC-45170), inhibits the processivity of telomerase with preferential DNA damage on telomeres. |
| PC-63060 |
BRACO-19
Telomerase inhibitor
|
BRACO-19 is a potent small molecule Telomerase inhibitor (IC50=115 nM) that inhibits expression of human telomerase reverse transcriptase (hTERT). |
| PC-63059 |
GTC365
Telomerase inhibitor
|
GTC-365 (NSC 177365) is a small drug-like pharmacological chaperone that induces cancer cell death by restoring tertiary DNA structures in mutant human telomerase reverse transcriptase (hTERT) promoters. |
| PC-63058 |
GTC365 hydrochloride
Telomerase inhibitor
|
GTC-365 (NSC 177365) is a small drug-like pharmacological chaperone that induces cancer cell death by restoring tertiary DNA structures in mutant human telomerase reverse transcriptase (hTERT) promoters. |
| PC-63056 |
MST-312
Telomerase inhibitor
|
MST-312 (Telomerase Inhibitor IX) is a potent, reversible telomerase inhibitor that effectively reduces telomere length and inhibits proliferation in U937 cells at 1 uM. |
| PC-62233 |
FJ 5002
Telomerase inhibitor
|
FJ 5002 is a potent telomerase inhibitor with IC50 of 2 uM, a close derivative of MKT077. |
| PC-62154 |
TMPyP4 tosylate
Telomerase inhibitor
|
TMPyP4 tosylate (TMP1363) is a potent inhibitor of human telomerase with IC50 of 6.5 uM. |
| PC-70273 |
6-thio-dG
Telomerase inhibitor
|
6-thio-dG (NSC 71261) is a nucleoside analogue that induces telomere dysfunction in telomerase-positive human cancer cells, but not in telomerase-negative cells. |
| PC-45170 |
BIBR-1532
Telomerase inhibitor
|
BIBR-1532 is a potent and selective telomerase inhibitor with IC50 of 5 uM. |
| PC-47447 |
Cycloastragenol
Telomerase activator
|
A natural tetracyclic triterpenoid that is a potent telomerase activator. |
| PC-21933 |
RHPS4
Telomerase inhibitor
|
RHPS4 is a potent telomerase inhibitor with IC50 of 0.33 uM, RHPS4 is a G-quadruplex (G4) ligand. |
| PC-21932 |
APOD53
TRF2 inhibitor
|
APOD53 is a specific, covalent cyclic peptide binder of TRF2 TRFH domain, prevents recruitment of RTEL1 and SLX4 to TRF2 in cells, impairs cancer cell growth. |
