FJ 5002 |CAS:247129-77-7 Probechem Biochemicals

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Chemical Structure : FJ 5002

FJ 5002 (FJ5002)

Catalog No.: PC-62233Not For Human Use, Lab Use Only.

FJ 5002 is a potent telomerase inhibitor with IC50 of 2 uM, a close derivative of MKT077.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FJ 5002 is a potent telomerase inhibitor with IC50 of 2 uM, a close derivative of MKT077.
FJ 5002 results in population-doubling dependent changes characterized by progressive telomere erosion.

Physicochemical Properties

M.Wt	452.046
Formula	C20H22ClN3OS3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-ethyl-2-((E)-((E)-3-ethyl-5-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)-4-methylthiazol-3-ium chloride

References

1. Naasani I, et al. Cancer Res. 1999 Aug 15;59(16):4004-11.

2. Yamori T. Cancer Chemother Pharmacol. 2003 Jul;52 Suppl 1:S74-9.

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FJ 5002 (FJ5002)

Biological Activity

Physicochemical Properties

References

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