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Chemical Structure : DIZ-3
Catalog No.: PC-38838Not For Human Use, Lab Use Only.
DIZ-3 is a dimeric aryl-substituted imidazole as a selective multimeric G-quadruplex (G4) ligand, intercalates into the G4-G4 interface, induces cell cycle arrest and apoptosis, and inhibits cell proliferation in alternative lengthening of telomere (ALT) cancer cell lines, via targeting telomeric multimeric G4.
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DIZ-3 is a dimeric aryl-substituted imidazole as a selective multimeric G-quadruplex (G4) ligand, intercalates into the G4-G4 interface, induces cell cycle arrest and apoptosis, and inhibits cell proliferation in alternative lengthening of telomere (ALT) cancer cell lines, via targeting telomeric multimeric G4.
| M.Wt | 746.911 | |
| Formula | C46H44F2N8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ming-Hao Hu, et al. Eur J Med Chem. 2020 Jan 15;186:111891.
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