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MST-312

Chemical Structure : MST-312

CAS No.: 368449-04-1

MST-312 (Telomerase Inhibitor IX, MST312)

Catalog No.: PC-63056Not For Human Use, Lab Use Only.

MST-312 (Telomerase Inhibitor IX) is a potent, reversible telomerase inhibitor that effectively reduces telomere length and inhibits proliferation in U937 cells at 1 uM.

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Biological Activity

MST-312 (Telomerase Inhibitor IX) is a potent, reversible telomerase inhibitor that effectively reduces telomere length and inhibits proliferation in U937 cells at 1 uM.
MST-312 exertes a dose-dependent short-term cytotoxic effect on APL cells, with G2/M cell cycle arrest, and induces apoptosis of APL cells in caspase-mediated manner.
MST-312 also suppresses HSV replication at multiple steps of viral infection.

Physicochemical Properties

M.Wt 380.35
Formula C20H16N2O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N,N'-1,3-Phenylenebis[2,3-dihydroxybenzamide]

References

1. Seimiya H, et al. Cancer Cell. 2005 Jan;7(1):25-37.

2. Fatemi A, et al. Tumour Biol. 2015 Nov;36(11):8425-37.

3. Haberichter J, et al. J Virol. 2015 Oct;89(19):9804-16.

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