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Chemical Structure : BRD-7880
Catalog No.: PC-61195Not For Human Use, Lab Use Only.
BRD-7880 (BRD7880) potent and highly specific inhibitor of Aurora B and Aurora C with IC50 of 7 and 12 nM respectively, with less activity against Aurora A (IC50>2 uM).
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BRD-7880 (BRD7880) potent and highly specific inhibitor of Aurora B and Aurora C with IC50 of 7 and 12 nM respectively, with less activity against Aurora A (IC50>2 uM).
BRD-7880 is far more selective than tozasertib (VX-680), substantially inhibiting (to < 25% control activity) only AURKB and AURKC in a panel of 308 kinases.
| M.Wt | 590.677 | |
| Formula | C32H38N4O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yu C, et al. Nat Biotechnol. 2016 Apr;34(4):419-23.
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