BRD6257

Chemical Structure : BRD6257

Catalog No.: PC-24296Not For Human Use, Lab Use Only.

BRD6257 is a potent, selective serine/threonine phosphatase PPM1D (Wip1, PP2Cδ) inhibitor with IC50 of 5 nM in LC-MS p38 MAPK assays.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

BRD6257 is a potent, selective serine/threonine phosphatase PPM1D (Wip1, PP2Cδ) inhibitor with IC50 of 5 nM in LC-MS p38 MAPK assays.
Oral administration of BRD6257 inhibits PPM1D and activates the p53 pathway in vivo comparable to GSK2830371.

Physicochemical Properties

M.Wt	550.53
Formula	C24H22F4N6O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S)-3-(3,3-difluorocyclopentyl)-N-(4-(difluoromethyl)phenyl)-2-((7-(5-methyloxazol-2-yl)-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)amino)propanamide

References

1. Shaw S, et al. iScience. 2025 Feb 20;28(3):112069.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

BRD6257

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.