Chemical Structure : BRM014
CAS No.:
2270879-17-7
BRM014
(BRM-014, Dual BRM and BRG1 inhibitor 14)
Catalog No. : PC-35746Not For Human Use, Lab Use Only.
BRM014 (BRM-014) is a potent, orally active inhibitor of Brahma Homolog (BRM)/SMARCA2 and Brahma-related gene 1 (BRG1) with IC50 of <5 nM for both.
Packing Price Stock Quantity 2 mg $158 In stock 0 1 2 3 4 5 5 mg $258 In stock 0 1 2 3 4 5 10 mg $398 In stock 0 1 2 3 4 5 25 mg $598 In stock 0 1 2 3 4 5 50 mg Get quote 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-3574601
Biological Activity
BRM014 (BRM-014) is a potent, orally active inhibitor of Brahma Homolog (BRM)/SMARCA2 and Brahma-related gene 1 (BRG1 ) with IC50 of <5 nM for both.
Physicochemical Properties
M.Wt
318.274
Formula
C11H9F3N4O2S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1-(3-(difluoromethyl)isothiazol-5-yl)-3-(2-fluoro-5-(hydroxymethyl)pyridin-4-yl)urea
References
1. Papillon JPN, et al. J Med Chem. Mol Cancer Res.
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