Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : BTZO-1
CAS No.: 99420-15-2
Catalog No.: PC-35107Not For Human Use, Lab Use Only.
BTZO-1 is a cardioprotective agent and Macrophage migration inhibitory factor (MIF) activator, binds to MIF with Kd of 68.6 nM, regulates ARE-mediated gene expression.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $188 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
BTZO-1 is a cardioprotective agent and Macrophage migration inhibitory factor (MIF) activator, binds to MIF with Kd of 68.6 nM, regulates ARE-mediated gene expression.
BTZO-1 activates the GST Ya gene ARE by interacting with MIF.
BTZO-1 induced expression of cytoprotective proteins such as heme oxygenase-1 (HO-1) and suppressed oxidative stress-induced cardiomyocyte apoptosis via binding to macrophage migration inhibitory factor (MIF).
| M.Wt | 240.28 | |
| Formula | C13H8N2OS | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one |
|
1. Kimura H, et al. Chem Biol. 2010 Dec 22;17(12):1282-94.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
