BX-2819 | HSP90 inhibitor | Probechem Biochemicals

Chemical Structure : BX-2819

BX-2819 (BX2819)

Catalog No.: PC-21297Not For Human Use, Lab Use Only.

BX-2819 is a potent, selective Hsp90 inhibitor with KD of 16.4 nM for human Hsp90α, also is a potent B. burgdorferi high-temperature protein G (Bb HtpG) with KD of 12 nM.

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Biological Activity

BX-2819 is a potent, selective Hsp90 inhibitor with KD of 16.4 nM for human Hsp90α, also is a potent B. burgdorferi high-temperature protein G (Bb HtpG) with KD of 12 nM.

Physicochemical Properties

M.Wt	428.51
Formula	C21H24N4O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl (4-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-thioxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)benzyl)carbamate

References

1. Dave L Carlson, et al. Cell Chem Biol. 2023 Oct 26:S2451-9456(23)00340-9.

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BX-2819 (BX2819)

Biological Activity

Physicochemical Properties

References

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