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Balixafortide

Chemical Structure : Balixafortide

CAS No.: 1051366-32-5

Balixafortide (POL6326;POL-6326)

Catalog No.: PC-61293Not For Human Use, Lab Use Only.

Balixafortide (POL6326) is a potent, selective, peptidic CXCR4 antagonist that interferes with the tumor-protective microenvironment and sensitizes tumor cells to chemotherapy.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Balixafortide (POL6326) is a potent, selective, peptidic CXCR4 antagonist that interferes with the tumor-protective microenvironment and sensitizes tumor cells to chemotherapy.
Balixafortide (POL6326) induces efficient mobilization of HSPCs (hematopoietic stem and progenitor cell) in clinical trails.

Physicochemical Properties

M.Wt 1782.029
Formula C80H112N22O21S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Ala-cys-ser-ala-pro-arg-tyr-cys-tyr-gln-lys-pro-pro-tyr-his cyclic (2->9)-disulfide

References

1. Karpova D, et al. J Transl Med. 2017 Jan 3;15(1):2.

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