Chemical Structure : Bantag-1 trifluoroacetate
CAS No.:
1972659-15-6
Bantag-1 trifluoroacetate
Catalog No.: PC-61215Not For Human Use, Lab Use Only.
Bantag-1 trifluoroacetate is a potent, highly selective, peptide bombesin receptor subtype-3 (BRS-3) antagonist with IC50 of 2-8 nM for human and rodent BRS-3.
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
Bantag-1 trifluoroacetate is a potent, highly selective, peptide bombesin receptor subtype-3 (BRS-3) antagonist with IC50 of 2-8 nM for human and rodent BRS-3.
Bantag-1 trifluoroacetate displays 1000-fold selectivity over hNMBR and hGRPR.
Bantag-1 trifluoroacetate increases food intake and produces an obesity phenotype in mice.
Physicochemical Properties
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M.Wt
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Formula
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C48H73N8O7 · xC2HF3O2
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20 °C 12 Months; 4°C 6 Months
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- In Solvent
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-80 °C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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Boc-Phe-His-4-amino-5-cyclohexyl-2,4,5-trideoxypentonyl-Leu-(3-dimethylamino) benzylamide N-methylammonium trifluoroacetate salt
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References
1. Moreno P, et al. J Pharmacol Exp Ther. 2013 Oct;347(1):100-16.
2. Guan XM, et al. Cell Metab. 2010 Feb 3;11(2):101-12.
3. Feng Y, et al. Endocrinology. 2011 Nov;152(11):4106-15.
4. Nakamura T, et al. Biochem Pharmacol. 2016 Sep 1;115:64-76.
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