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Basimglurant

Chemical Structure : Basimglurant

CAS No.: 802906-73-6

Basimglurant (RG-7090, RO-4917523, RG7090)

Catalog No.: PC-26042Not For Human Use, Lab Use Only.

Basimglurant (RG7090) is a potent, selective and orally available mGlu5 receptor (mGluR5) negative allosteric modulator (NAM) with Kd of 1.1 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Basimglurant (RG7090) is a potent, selective and orally available mGlu5 receptor (mGluR5) negative allosteric modulator (NAM) with Kd of 1.1 nM.

Physicochemical Properties

M.Wt 325.77
Formula C18H13ClFN3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Chloro-4-((1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-yl)ethynyl)pyridine

References

1. Lindemann L, et al. J Pharmacol Exp Ther. 2015 Apr;353(1):213-33.

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