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Batimastat

Chemical Structure : Batimastat

CAS No.: 130370-60-4

Batimastat (BB94, BB-94)

Catalog No.: PC-23343Not For Human Use, Lab Use Only.

Batimastat (BB94) is a potent broad spectrum matrix metalloproteinase (MMP) inhibitor with IC50 of 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Batimastat (BB94) is a potent broad spectrum matrix metalloproteinase (MMP) inhibitor with IC50 of 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3, respectively.

Physicochemical Properties

M.Wt 477.64
Formula C23H31N3O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,3R)-N1-Hydroxy-3-isobutyl-N4-((S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl)-2-((thiophen-2-ylthio)methyl)succinamide

References

1. Davies B, et al. Cancer Res. 1993 May 1;53(9):2087-91.

2. Botos I, et al. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2749-54.

3. Watson SA, et al. Cancer Res. 1995 Aug 15;55(16):3629-33.

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