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Benzarone

Chemical Structure : Benzarone

CAS No.: 1477-19-6

Benzarone (NSC 82134)

Catalog No.: PC-35159Not For Human Use, Lab Use Only.

Benzarone (NSC 82134) is a small molecule inhibitor of Eyes Absen (EYA) protein tyrosine phosphatase activity (IC50=17 uM, EYA3), exhibits selectivity for EYA over PTP1B.

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Biological Activity

Benzarone (NSC 82134) is a small molecule inhibitor of Eyes Absen (EYA) protein tyrosine phosphatase activity (IC50=17 uM, EYA3), exhibits selectivity for EYA over PTP1B;.
Benzarone (NSC 82134) inhibits both tumor angiogenesis and tumor growth.

Physicochemical Properties

M.Wt 266.296
Formula C17H14O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2-ethyl-1-benzofuran-3-yl)-(4-hydroxyphenyl)methanone

References

1. Wang Y, et al. Mol Cancer Ther. 2018 May 25. pii: molcanther.0057.2018.

2. Tadjuidje E, et al. PLoS One. 2012;7(4):e34806.

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