Chemical Structure : Berberine
CAS No.: 2086-83-1
Catalog No.: PC-26655Not For Human Use, Lab Use Only.
Berberine (Natural Yellow 18) is an alkaloid isolated from the Chinese herbal medicine Huanglian, induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase, disrupts G-quadruplex (G4)-STAT1 interaction and synergizes with olaparib to drive cancer cell death, shows antineoplastic properties, also is a potent USP22 inhibitor, effectively suppresses Wnt pathway activation and CRC cell proliferation
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 500 mg | $78 | In stock | |
| 1 g | $118 | In stock | |
| 5 g | Get quote |
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Berberine (Natural Yellow 18) is an alkaloid isolated from the Chinese herbal medicine Huanglian, induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase, disrupts G-quadruplex (G4)-STAT1 interaction and synergizes with olaparib to drive cancer cell death, shows antineoplastic properties, also is a potent USP22 inhibitor, effectively suppresses Wnt pathway activation and CRC cell proliferation.
| M.Wt | 336.37 | |
| Formula | C20H18NO4+ | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium |
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1. Cai Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan;68(1):53-62.
2. Wang Y, et al. Nucleic Acids Res. 2026 May 5;54(9):gkag383.
3. Gang Xu, et al. Phytomedicine. 2026 Mar:152:157765.

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