Bicuculline | GABAA antagonist | Probechem Biochemicals

Chemical Structure : Bicuculline

CAS No.: 485-49-4

Bicuculline ((+)-Bicuculline)

Catalog No.: PC-28342Not For Human Use, Lab Use Only.

Bicuculline ((+)-Bicuculline) is a competing neurotransmitter GABAA receptor antagonist with IC50 of 2 uM, shows neuroprotective and anticonvulsant activity.

Packing	Price	Stock
50 mg	$58	In stock
100 mg	$88	In stock
250 mg	$138	In stock
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Biological Activity

Bicuculline ((+)-Bicuculline) is a competing neurotransmitter GABAA receptor antagonist with IC50 of 2 uM, shows neuroprotective and anticonvulsant activity.

Physicochemical Properties

M.Wt	367.36
Formula	C20H17NO6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-6-((S)-6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-[1,3]dioxolo[4,5-e]isobenzofuran-8(6H)-one

References

1. Johnston GA. Br J Pharmacol. 2013;169(2):328-336.

2. Huang SH, et al. Eur J Pharmacol. 2003;464(1):1-8.

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Bicuculline ((+)-Bicuculline)

Biological Activity

Physicochemical Properties

References

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