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Bimoclomol

Chemical Structure : Bimoclomol

CAS No.: 130493-03-7

Bimoclomol (BRLP-42, BRLP42)

Catalog No.: PC-60546Not For Human Use, Lab Use Only.

Bimoclomol (BRLP-42) is a potent heat shock protein coinducer, increases an inducible member of the heat shock protein 70 family (HSP70) and cytoprotect in vitro, reduces infarct size in a rat model of ischemia and reperfusion.

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    Biological Activity

    Bimoclomol (BRLP-42) is a potent heat shock protein coinducer, increases an inducible member of the heat shock protein 70 family (HSP70) and cytoprotect in vitro, reduces infarct size in a rat model of ischemia and reperfusion.
    Bimoclomol facilitates the formation of chaperone molecules in eukaryotic cells by inducing or amplifying expression of heat-shock genes.

    Physicochemical Properties

    M.Wt 297.783
    Formula C14H20ClN3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-hydroxy-3-(1-piperidinyl) propoxy]-3-pyridinecarboximidoil-chloride

    References

    1. Vígh L, et al. Nat Med. 1997 Oct;3(10):1150-4.

    2. Erdö F, et al. Brain Res Bull. 1998;45(2):163-6.

    3. Nánási PP, et al. Br J Pharmacol. 2000 Apr;129(7):1405-12.

    4. Lubbers NL, et al. Eur J Pharmacol. 2002 Jan 18;435(1):79-83.

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