Catalog No.: PC-22347Not For Human Use, Lab Use Only.
Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function.
Blebbistatin is a potent and selective non-muscle myosin II (NMII) inhibitor with IC50 of 0.5-5 uM. Blebbistatin inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Blebbistatin inhibits pancreatic adenocarcinoma cellular invasiveness; inhibits some myosin II-independent processes. Blebbistatin inhibits other activities in the absence of myosin II.
