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Cat. No. Product Name CAS No. Information
PC-60047

Mavacamten

1642288-47-8 Mavacamten (SAR-439152, MYK-461) is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain.
PC-72702

MT-134

MT-134 (Skeletostatin MT-134) is a selective skeletal myosin II (SkMII) inhibitor with Ki of 0.48 uM, 40- to 170-fold for SkMII over all other myosin II family members.
PC-38077

Aficamten

2364554-48-1 Aficamten (CK-274) is a novel next-generation cardiac myosin inhibitor (IC50 =1.4 uM) for treatment of hypertrophic cardiomyopathy.
PC-36046

Myokinasib

Myokinasib is a mixed-type, selective inhibitor of Myosin Light Chain Kinase 1 (MLCK1) with IC50 of 7.9 uM, can bind to the free enzyme and the enzyme-substrate complex.
PC-43535

Blebbistatin S enantiomer

856925-71-8 Blebbistatin S enantiomer ((S)-(-)-Blebbistatin) is the S enantiomer of blebbistatin, which is a potent and selective myosin II inhibitor with IC50 of 0.5-5 uM.
PC-63125

BHC

342387-19-3 BHC (Myosin inhibitor BHC) is a small-molecule screen of skeletal muscle myosin inhibitor that suppresses movements without affecting membrane currents.
PC-62887

ML-9 hydrochloride

105637-50-1 ML-9 hydrochloride is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM, inhibits Store-operated Ca2+ entry (SOCE) in a variety of cell lines.

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