| Cat. No. |
Product Name |
Information |
| PC-23164 |
Myokinasib-II
MLCK inhibitor
|
Myokinasib-II is a potent and highly selective myosin light-chain kinase (MLCK) chemical probe inhibitor with IC50 of 4.4 uM for MLCK-1. |
| PC-23162 |
ML-9 free base
MLCK inhibitor
|
ML-9 is a potent, ATP-competitive myosin light chain kinase (MLCK) inhibitor with Ki of 3.8 uM, inhibits Store-operated Ca2+ entry (SOCE) in a variety of cell lines. |
| PC-23161 |
ML-7 hydrochloride
MLCK inhibitor
|
ML-7 hydrochloride is a potent, specific myosin light chain kinase (MLCK) inhibitor with IC50 of 300 nM, also inhibits YAP/TAZ. |
| PC-22762 |
CK-586
Cardiac myosin inhibitor
|
CK-4021586 (CK-586) is a potent, selective and oral cardiac myosin inhibitor, inhibits the ATPase activity of two-headed heavy meromyosin (HMM) but not single-headed subfragment-1. |
| PC-22347 |
Blebbistatin
Myosin II inhibitor
|
Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. |
| PC-22342 |
Divertin
MLCK1 inhibitor
|
Divertin (NSC55937, Tetraformaltrisazine) a small molecule MLCK1 inhibitor, diverts MLCK1 from the PAMR, does not interfere with MLCK enzymatic activity, prevent MLCK-mediated intestinal barrier loss in vitro and in vivo. |
| PC-21413 |
Myosin inhibitor F10
Cardiac-myosin inhibitor
|
Cardiac-myosin inhibitor F10 is a cardiac-myosin specific and allosteric inhibitor with IC50 of 23 uM on actomyosin ATPase activity. |
| PC-43535 |
Blebbistatin S enantiomer
|
Blebbistatin S enantiomer ((S)-(-)-Blebbistatin) is the S enantiomer of blebbistatin, which is a potent and selective myosin II inhibitor with IC50 of 0.5-5 uM. |
