BTS | myosin II ATPase inhibitor | Probechem Biochemicals

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Chemical Structure : BTS

CAS No.: 1576-37-0

BTS (myosin II ATPase inhibitor, N-Tosylbenzylamine)

Catalog No.: PC-45036Not For Human Use, Lab Use Only.

BTS is a highly specific myosin II ATPase inhibitor, inhibits the Ca2+-stimulated S1 ATPase, and reversibly blocked gliding motility.

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Biological Activity

BTS is a highly specific myosin II ATPase inhibitor, inhibits the Ca2+-stimulated S1 ATPase, and reversibly blocked gliding motility.
BTS inhibits isometric Ca2+-activated tension with IC50 of 3 uM in glycerol-extracted fibres from rabbit psoas muscle;.
BTS is specific and has no activity for platelet myosin II.

Physicochemical Properties

M.Wt	261.3394
Formula	C14H15NO2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzenesulfonamide, 4-methyl-N-(phenylmethyl)-

References

1. Cheung A, et al. Nat Cell Biol. 2002 Jan;4(1):83-8.

2. Blair DR, et al. Am J Physiol Endocrinol Metab. 2009 May;296(5):E993-E1002.

3. Abi-Gerges N, et al. J Mol Cell Cardiol. 2013 Nov;64:108-19.

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BTS (myosin II ATPase inhibitor, N-Tosylbenzylamine)

Biological Activity

Physicochemical Properties

References

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