Chemical Structure : Blebbistatin S enantiomer
CAS No.: 856925-71-8
Catalog No.: PC-43535Not For Human Use, Lab Use Only.
Blebbistatin S enantiomer ((S)-(-)-Blebbistatin) is the S enantiomer of blebbistatin, which is a potent and selective myosin II inhibitor with IC50 of 0.5-5 uM.
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25 mg | $178 | In stock | |
50 mg | $398 | In stock | |
100 mg | $688 | In stock | |
500 mg | Get quote |
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Blebbistatin S enantiomer ((S)-(-)-Blebbistatin) is the S enantiomer of blebbistatin, which is a potent and selective myosin II inhibitor with IC50 of 0.5-5 uM; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly, inhibits pancreatic adenocarcinoma cellular invasiveness; inhibits some myosin II-independent processes and that blebbistatin inhibits other activities in the absence of myosin II.
M.Wt | 292.3318 | |
Formula | C18H16N2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: 5.2 mg/mL (Need ultrasonic and warming) |
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Chemical Name/SMILES |
4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aS)- |
1. Straight AF, et al. Science. 2003 Mar 14;299(5613):1743-7.
2. Abe M, et al. J Biol Chem. 2003 Nov 28;278(48):47707-12.
3. Duxbury MS, et al. Biochem Biophys Res Commun. 2004 Jan 23;313(4):992-7.
4. Shu S, et al. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1472-7.
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