 
                Chemical Structure : Bobcat339
CAS No.: 2280037-51-4
Catalog No.: PC-36114Not For Human Use, Lab Use Only.
Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
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	Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
	Bobcat339 is a useful tool for investigation of epigenetics and serve as a starting point for new therapeutics that target DNA methylation and gene transcription.
| M.Wt | 297.742 | |
| Formula | C16H12ClN3O | |
| Appearance | Solid | |
| Storage | 
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| Solubility | 10 mM in DMSO | |
| Chemical Name/SMILES | 1-([1,1'-biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one | |
1. Chua GNL, et al. ACS Med Chem Lett. 2019 Jan 31;10(2):180-185.

 
                 
                 
                 
                 
                 
                 
                 
                 
            
            
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