| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-36114 |
Bobcat339
|
2280037-51-4 |
Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a. |
| PC-43810 |
SGI-1027
|
1020149-73-8 |
SGI-1027 (SGI1027) is a potent inhibitor of DNA methyltransferase (DNMT) with IC50s of 6-12.5 uM for DNMT1, DNMT3A, and DNMT3B. |
| PC-38486 |
SW155246
|
420092-79-1 |
SW155246 is a potent, selective antagonis/inhibitor of DNA methyltransferase DNMT1 with IC50 of 1.2 uM against hDNMT1, 30-fold preference versus human or murine DNMT3A or -3B (IC50=38 uM). |
| PC-73377 |
GSK3543105
|
2170139-57-6 |
GSK3543105 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 33 nM. |
| PC-73376 |
GSK3735967
|
2170136-86-2 |
GSK3735967 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 40 nM. |
| PC-72377 |
UHRF1 PHD inhibitor MLD4
|
922067-76-3 |
UHRF1 PHD inhibitor MLD4 is a specific compound that selectively inhibits the UHRF1-histone interaction (IC50=12.4 uM), targets the PHD finger of UHRF1, specifically disrupting histone H3 arginine 2 interactions with the PHD finger. |
| PC-72376 |
UHRF1 PHD inhibitor MLD5
|
946347-36-0 |
UHRF1 PHD inhibitor MLD5 is a specific compound that selectively inhibits the UHRF1-histone interaction (IC50=7.4 uM), targets the PHD finger of UHRF1, specifically disrupting histone H3 arginine 2 interactions with the PHD finger. |
