GSK3543105 | DNMT1 inhibitor | Probechem Biochemicals

Chemical Structure : GSK3543105

Catalog No.: PC-73377Not For Human Use, Lab Use Only.

GSK3543105 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 33 nM.

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Biological Activity

GSK3543105 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 33 nM.

M.Wt	464.588
Formula	C24H28N6O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((3,5-dicyano-4-ethyl-6-(4-(2-hydroxyethyl)-1,4-diazepan-1-yl)pyridin-2-yl)thio)-2-phenylacetamide

1. Horton JR, et al. Structure. 2022 Mar 28:S0969-2126(22)00090-9.