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GSK3735967

Chemical Structure : GSK3735967

CAS No.: 2170136-86-2

GSK3735967 (GSK 3735967)

Catalog No.: PC-73376Not For Human Use, Lab Use Only.

GSK3735967 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 40 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GSK3735967 is a potent, selective, non-nucleoside inhibitor of DNMT1 with IC50 of 40 nM.

Physicochemical Properties

M.Wt 477.631
Formula C25H31N7OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-amino-N-(4-(((3,5-dicyano-4-ethyl-6-(4-methyl-1,4-diazepan-1-yl)pyridin-2-yl)thio)methyl)benzyl)acetamide

References

1. Horton JR, et al. Structure. 2022 Mar 28:S0969-2126(22)00090-9.

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