Chemical Structure : Brevianamide F
CAS No.: 38136-70-8
Catalog No.: PC-42127Not For Human Use, Lab Use Only.
Brevianamide F (Cyclo(L-Pro-L-Trp)) is a naturally occurring 2,5-diketopiperazine that possess interesting breast cancer resistance protein (BCRP) inhibitory activity.
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Brevianamide F (Cyclo(L-Pro-L-Trp)) is a naturally occurring 2,5-diketopiperazine that possess interesting breast cancer resistance protein (BCRP) inhibitory activity.
Brevianamide F also shows agonism towards Ca(2+)-channel activity at 100 uM, and has potentiation for use in the treatment of cardiovascular dysfunction.
| M.Wt | 283.3251 | |
| Formula | C16H17N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-indol-3-ylmethyl)-, (3S,8aS)- |
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1. Jamie H, et al. J Pharm Pharmacol. 2002 Dec;54(12):1659-65.
2. Wauters I, et al. J Org Chem. 2015 Aug 21;80(16):8046-54.
3. Wollinsky B, et al. Org Biomol Chem. 2012 Dec 14;10(46):9262-70.

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