Chemical Structure : Brivanib alaninate
CAS No.:
649735-63-7
Brivanib alaninate
(BMS-582664, BMS582664)
Catalog No. : PC-42533Not For Human Use, Lab Use Only.
Brivanib alaninate is prodrug of Brivanib (BMS-582664), which is a dual inhibitor of VEGFR2 and FGFR1 with IC50 of 25 nM and 148 nM respectively.
Packing Price Stock Quantity 5 mg $128 In stock 0 1 2 3 4 5 10 mg $198 In stock 0 1 2 3 4 5 25 mg $328 In stock 0 1 2 3 4 5 50 mg $528 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4253301
Biological Activity
Brivanib alaninate is prodrug of Brivanib (BMS-582664), which is a dual inhibitor of VEGFR2 and FGFR1 with IC50 of 25 nM and 148 nM respectively.
Physicochemical Properties
M.Wt
441.4555
Formula
C22H24FN5O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
L-Alanine, (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-1-methylethyl ester
References
1. Cai ZW, et al. J Med Chem.
2. Huynh H, et al. Clin Cancer Res
3. Patel RR, et al. Eur J Cancer
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