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Chemical Structure : Bromocriptine mesylate
CAS No.: 22260-51-1
Catalog No.: PC-43160Not For Human Use, Lab Use Only.
Bromocriptine (CB-154) is a dopamine D2 receptor agonist (Ki=3 nM) and and various serotonin receptors, also inhibits the release of glutamate by reversing the glutamate GLT1 transporter.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $68 | In stock | |
| 250 mg | $118 | In stock | |
| 500 mg | $198 | In stock | |
| 1 g | Get quote |
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Bromocriptine (CB-154) is a dopamine D2 receptor agonist (Ki=3 nM) and and various serotonin receptors, also inhibits the release of glutamate by reversing the glutamate GLT1 transporter.
Bromocriptine (CB-154) decreases body fat in animal and human models and increases lean muscle mass, improves glucose intolerance and insulin resistance, and reduces triglycerides and free fatty acids.
Bromocriptine (CB-154) also induces apoptosis and decreases colony formation in AML cells, shows synergy with standard agents and selectivity for the leukemic cell.
Bromocriptine (CB-154) reduces hyperphagia and adiposity in rats with diet-induced obesity.
| M.Wt | 750.7001 | |
| Formula | C33H44BrN5O8S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 30 mg/mL |
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| Chemical Name/SMILES |
Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5α)-, methanesulfonate (1:1) |
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1. Shirasaki Y, et al. Eur J Pharmacol. 2010 Sep 15;643(1):48-57.
2. Oda T, et al. Eur J Pharmacol. 2008 Nov 19;598(1-3):27-31.
3. Wacker J, et al. Psychophysiology. 2006 Jul;43(4):372-81.
4. Liberante FG, et al. Oncotarget. 2016 Feb 9;7(6):6609-19.
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