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C-021

Chemical Structure : C-021

CAS No.: 864289-85-0

C-021 (C021)

Catalog No.: PC-62752Not For Human Use, Lab Use Only.

C-021 is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

C-021 is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.

Physicochemical Properties

M.Wt 467.658
Formula C27H41N5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-([1,4'-bipiperidin]-1'-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine

References

1. Yokoyama K, et al. Bioorg Med Chem. 2009 Jan 1;17(1):64-73.

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