C-021 dihydrochloride | CCR4 antagonist

Chemical Structure : C-021 dihydrochloride

CAS No.: 1784252-84-1

C-021 dihydrochloride (C021 dihydrochloride)

Catalog No.: PC-61983Not For Human Use, Lab Use Only.

C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively..

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$328	In stock
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Biological Activity

C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.

Physicochemical Properties

M.Wt	540.57
Formula	C27H41N5O2.2HCl
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-([1,4'-bipiperidin]-1'-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine dihydrochloride

References

1. Yokoyama K, et al. Bioorg Med Chem. 2009 Jan 1;17(1):64-73.

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C-021 dihydrochloride (C021 dihydrochloride)

Biological Activity

Physicochemical Properties

References

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