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Chemical Structure : C1s inhibitor A1
CAS No.: 1016866-61-7
Catalog No.: PC-21586Not For Human Use, Lab Use Only.
C1s inhibitor A1 is a selective, competitive inhibitor of complement component C1s with binding Kd of 9.8 uM, competitively inhibits its activity with Ki of 5.8 uM.
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|---|---|---|---|
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
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| 100 mg | Get quote |
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C1s inhibitor A1 is a selective, competitive inhibitor of complement component C1s with binding Kd of 9.8 uM, competitively inhibits its activity with Ki of 5.8 uM.
C1s inhibitor A1 dose-dependently inhibits CP activation by heparin-induced immune complexes, CP-driven lysis of Ab-sensitized sheep erythrocytes, CP activation in a pathway-specific ELISA, and cleavage of C2 by C1s.
| M.Wt | 281.36 | |
| Formula | C16H19N5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
6-(4-phenylpiperazin-1-yl)pyridine-3-carboximidamide |
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1. Xu X, et al. J Immunol. 2023. Dec 27:ji2300630.
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