C450-0730 | LuxN antagonist | Probechem Biochemicals

Chemical Structure : C450-0730

CAS No.: 1036730-46-7

C450-0730 (LuxN antagonist)

Catalog No.: PC-62656Not For Human Use, Lab Use Only.

C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM.

Packing	Price	Stock
5 mg	$228	In stock
10 mg	$358	In stock
25 mg	$558	In stock
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Biological Activity

C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM.
C450-0730 competes for the AI-1 binding site of LuxN.
Inhibition for mutant LuxN G271D, R245L, and S184N is similar to that required to inhibit wild-type LuxN.

Physicochemical Properties

M.Wt	478.004
Formula	C23H28ClN3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((1-acetylindoline)-5-sulfonamido)-N-(4-chlorobenzyl)-4-methylpentanamide

References

1. Swem LR, et al. Cell. 2008 Aug 8;134(3):461-73.

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