CARM1 inhibitor 9 |CAS:2180931-09-1 Probechem Biochemicals

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Chemical Structure : CARM1 inhibitor 9

CARM1 inhibitor 9

Catalog No.: PC-35042Not For Human Use, Lab Use Only.

CARM1 inhibitor 9 is a potent, selective inhibitor of arginine methyltransferase 1 (CARM1, PRMT4) with IC50 of 94 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CARM1 inhibitor 9 is a potent, selective inhibitor of arginine methyltransferase 1 (CARM1, PRMT4) with IC50 of 94 nM.
CARM1 inhibitor 9 displays 20-fold selective for CARM1 over PRMT6 and highly selective over PRMT1, PRMT3, PRMT8 as well as PRMT5 and PRMT7.
CARM1 inhibitor 9 is a useful tool for studying the role of CARM1 in health and disease.

Physicochemical Properties

M.Wt	326.282
Formula	C15H24BrN3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-bromobenzyl)-1-(2-(methylamino)ethyl)piperidin-4-amine

References

1. Kaniskan HÜ, et al. Medchemcomm. 2016 Sep 1;7(9):1793-1796.

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